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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
41.52
Human Site:
S292
Identified Species:
65.24
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
S292
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Chimpanzee
Pan troglodytes
XP_510014
764
85553
S381
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
S291
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Dog
Lupus familis
XP_547862
675
77214
S292
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
S292
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Rat
Rattus norvegicus
Q5U2Y3
576
65604
S255
P
C
K
E
A
G
L
S
F
R
K
G
D
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
S292
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Chicken
Gallus gallus
Q5ZJ00
468
52501
V150
Q
G
M
V
S
I
K
V
I
P
N
Q
Q
S
R
Frog
Xenopus laevis
NP_001085267
675
76810
S292
K
G
G
A
A
E
K
S
G
L
L
H
E
G
D
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S294
K
G
G
A
A
E
R
S
G
L
L
H
E
G
D
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
K149
T
N
G
V
V
T
M
K
I
I
P
R
P
Q
S
Fruit Fly
Dros. melanogaster
Q24210
898
100893
Q532
H
G
G
M
I
H
R
Q
A
T
L
H
V
G
D
Honey Bee
Apis mellifera
XP_393395
1033
115664
S630
R
G
G
A
A
D
K
S
G
L
L
H
E
G
D
Nematode Worm
Caenorhab. elegans
P54936
961
108794
Q583
H
G
G
M
I
H
R
Q
A
T
L
H
V
G
D
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
S586
R
G
G
M
A
E
K
S
G
L
L
H
E
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
100
93.3
6.6
40
86.6
40
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
33.3
100
100
13.3
46.6
100
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
74
0
0
0
14
0
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
80
% D
% Glu:
0
0
0
7
0
60
0
0
0
0
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
87
87
0
0
7
0
0
67
0
0
7
0
80
0
% G
% His:
14
0
0
0
0
14
0
0
0
0
0
80
0
0
0
% H
% Ile:
0
0
0
0
14
7
0
0
14
7
0
0
0
7
0
% I
% Lys:
54
0
7
0
0
0
67
7
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
67
80
0
0
0
7
% L
% Met:
0
0
7
20
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
7
7
0
7
0
0
% P
% Gln:
7
0
0
0
0
0
0
14
0
0
0
7
7
7
0
% Q
% Arg:
14
0
0
0
0
0
20
0
0
7
0
7
0
0
7
% R
% Ser:
0
0
0
0
7
0
0
74
0
0
0
0
0
7
7
% S
% Thr:
7
0
0
0
0
7
0
0
0
14
0
0
0
0
0
% T
% Val:
0
0
0
14
7
0
0
7
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _